There can be no turning back.
没有回头路了。
以上为机器翻译结果，长、整句建议使用 人工翻译 。
We said we would do it—there can be no turning back.
我们说过要干这事，不能反悔。
《牛津词典》
Because of the prospects in wide application of this grinding wheel, there can be no turning back in developing this wheel in our country.
鉴于它极其广阔的应用前景，国内在推广应用超硬磨料砂轮时也必将大力开发此种单层钎焊砂轮。
youdao
The best he can hope for is that the peace talks with the ELN and the FARC both advance to such a stage that there can be no turning back.
BBC: Colombia rebels in Christmas truce
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